1H-indazole, 4,5-dichloro-
1H-indazole, 4,5-dichloro-
CAS: 1020243-02-0
Molecular Formula: C7H4Cl2N2
1H-indazole, 4,5-dichloro- - Names and Identifiers
| Name | 1H-indazole, 4,5-dichloro- |
| Synonyms | AgrelideImpurity19 Anagrelide Impurity 19 4,5-Dichloro-1H-indazole 1H-Indazole, 4,5-dichloro- 1H-indazole, 4,5-dichloro- |
| CAS | 1020243-02-0 |
| InChI | InChI=1S/C7H4Cl2N2/c8-5-1-2-6-4(7(5)9)3-10-11-6/h1-3H,(H,10,11) |
1H-indazole, 4,5-dichloro- - Physico-chemical Properties
| Molecular Formula | C7H4Cl2N2 |
| Molar Mass | 187.03 |
| Storage Condition | Room Temprature |
1H-indazole, 4,5-dichloro- - Introduction
4,5-dichloro-lH-indazole is an organic compound with the chemical formula C7H4Cl2N2. The following is an introduction to its nature, use, preparation and safety information:
Nature:
-4,5-dichloro-1H-indazole is a colorless to light yellow solid with a special aromatic odor.
-It is stable at room temperature, but sensitive to light, heat and air.
-Its density is 1.6g/cm³, its melting point is 77-80 ℃, and its boiling point is 180-185 ℃.
-The compound is poorly soluble in water, but soluble in many organic solvents such as ethanol and dimethylformamide.
Use:
-4,5-Dichloro-1H-indazole is widely used in the field of pesticides as a synthetic intermediate of heterocyclocompounds.
-It can also be used in the field of biomedicine for the synthesis of biologically active compounds.
-In addition, it is also used in the fields of dyes, catalysts and organic laser materials.
Preparation Method:
The preparation of-4,5-dichloro-1H-indazole can be obtained by reacting indole chloride with sulfuryl chloride. First, indole chloride and thionyl chloride are reacted in an organic solvent, followed by collision elimination reaction under mild conditions to obtain the target product.
Safety Information:
-4,5-dichloro -1H-indazole is an organic compound, which may be irritating and damaging, and safety should be paid attention to when using or operating.
-Wear appropriate personal protective equipment such as goggles, gloves and protective clothing when used.
-Avoid direct contact with skin, eyes and respiratory tract, and take care to avoid inhaling its dust or vapor.
-In case of accidental contact, rinse immediately with plenty of water and seek medical attention.
-When storing and using, follow the correct chemical handling method, and store it in a cool, dry, well-ventilated place, away from fire and flammable materials.
Please note that the above information is for reference only. When using or handling chemicals, you should follow the relevant regulations and safety operation guidelines in your region.
Nature:
-4,5-dichloro-1H-indazole is a colorless to light yellow solid with a special aromatic odor.
-It is stable at room temperature, but sensitive to light, heat and air.
-Its density is 1.6g/cm³, its melting point is 77-80 ℃, and its boiling point is 180-185 ℃.
-The compound is poorly soluble in water, but soluble in many organic solvents such as ethanol and dimethylformamide.
Use:
-4,5-Dichloro-1H-indazole is widely used in the field of pesticides as a synthetic intermediate of heterocyclocompounds.
-It can also be used in the field of biomedicine for the synthesis of biologically active compounds.
-In addition, it is also used in the fields of dyes, catalysts and organic laser materials.
Preparation Method:
The preparation of-4,5-dichloro-1H-indazole can be obtained by reacting indole chloride with sulfuryl chloride. First, indole chloride and thionyl chloride are reacted in an organic solvent, followed by collision elimination reaction under mild conditions to obtain the target product.
Safety Information:
-4,5-dichloro -1H-indazole is an organic compound, which may be irritating and damaging, and safety should be paid attention to when using or operating.
-Wear appropriate personal protective equipment such as goggles, gloves and protective clothing when used.
-Avoid direct contact with skin, eyes and respiratory tract, and take care to avoid inhaling its dust or vapor.
-In case of accidental contact, rinse immediately with plenty of water and seek medical attention.
-When storing and using, follow the correct chemical handling method, and store it in a cool, dry, well-ventilated place, away from fire and flammable materials.
Please note that the above information is for reference only. When using or handling chemicals, you should follow the relevant regulations and safety operation guidelines in your region.
Last Update：2024-04-09 21:01:54
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CAS: 1020243-02-0
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